-
Brain waste clearance to treat CAA: apolipoprotein J, and cholinergic and aginergic innervation of the smooth cells
According to Roxana Carare, MD PhD, at the University of Southampton, apolipoprotein J (also called clusterin) is being investigated for its role in chaperoning Amyloid Beta for brain waste clearance along the intramural periarterial pathway (IPAD). A second approach to improving amyloid beta clearance is via the cholinergic and aginergic innervation of the smooth cells…